Synthesis and evaluation of a tri-tyrosine decorated dextran MR contrast agent for vulnerable plaque detection.

Anne Beilvert,Roger Vassy,Emmanuelle Canet-Soulas,Olivier Rousseaux,Luc Picton,Didier Letourneur,Frédéric Chaubet

CHEMICAL COMMUNICATIONS（2011）

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摘要

This communication reports the synthesis, characterization and in vivo evaluation in mice of a new tri-tyrosine conjugated MR contrast agent, which may help to identify vulnerable plaques in atherosclerosis by targeting the lipid core.

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关键词

dextran mr contrast agent,contrast agent,tri-tyrosine

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