Comparative Analysis Of The Expression Of Metalloproteases And Their Inhibitors In Resected Crohn'S Disease And Complicated Diverticular Disease

Antonio Altadill,Noemí Eiró,Luis Ovidio González,Sara Junquera,José Manuel González-Quintana,María Rosario Sánchez,Alejandro Andicoechea,Cristina Saro,Luis Rodrigo,Francisco José Vizoso

INFLAMMATORY BOWEL DISEASES（2012）

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摘要

Background: Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), are expressed in the gastrointestinal tract by different cellular types. Nevertheless, the imbalance between MMPs and TIMPs plays an important role in the physiopathology of diverse intestinal inflammatory processes.

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关键词

MMP, TIMP, Crohn's disease, diverticulitis

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