A premenopausal woman with virilization secondary to an ovarian Leydig cell tumor

Virilizing ovarian tumors are rare neoplasms that may affect both women of reproductive age and postmenopausal women. This Case Study describes a young woman with longstanding amenorrhea and virilization and highlights the challenges and pitfalls in the diagnosis and choice of proper treatment for this uncommon cause of female hyperandrogenism.