Active immunization with proteolipid protein (190-209) induces ascending paralysing experimental autoimmune encephalomyelitis in C3H/HeJ mice.

Kerstin Göbel,Stefan Bittner,Tobias Ruck,Thomas Budde,Erhard Wischmeyer,Frank Döring,Heinz Wiendl,Sven G Meuth

Journal of Immunological Methods（2011）

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摘要

Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease of the central nervous system (CNS) that shares clinical and pathophysiological feature with multiple sclerosis (MS) and is commonly used as an animal model for the human disease.

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关键词

Active EAE,PLP,C3H

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