Comparison Of Co2 Generation (Bactec) And Viable-Count Methods To Determine The Postantibiotic Effect Of Antimycobacterial Agents Against Mycobacterium Avium Complex
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY(1998)
摘要
The postantibiotic effects (PAEs) of antimycobacterial agents determined with a BACTEC TB-460 instrument (CO2 production) and by a traditional viable-count method against Mycobacterium avium complex (MAC) were not significantly different (P > 0.05). The longest PAEs following a 2-h exposure to 2x the MIC were induced by amikacin (10.3 h), rifampin (9.7 h), and rifabutin (9.5 h), while the shortest PAEs resulted from clofazimine (1.7 h) and ethambutol (1.1 h) exposure. CO2 generation is a valid and efficient means of determining in vitro PAEs against MAC.
更多查看译文
关键词
carbon dioxide
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要