Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination

Ye He,Jin Young Kim,Jeffrey Dupree,Ambika Tewari,Carmen Melendez-Vasquez,John Svaren,Patrizia Casaccia

NATURE NEUROSCIENCE（2010）

引用 102|浏览14

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摘要

He et al . identify the transcription factor YY1 as being critical for peripheral myelination. YY1 phosphorylation by neuregulin is required for transcriptional activation of Egr2/Krox20, a critical regulator of peripheral myelination.

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transcription factor

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