Tumoral vascularization: physiopathology and therapeutic prospects]
BULLETIN DU CANCER(1997)
摘要
The Folkman's hypothesis postulates that tumor or metastase development is angiogenesis dependent. Since 1971, several lines of experimental data have supported this hypothesis in particular during the past months. A better understanding of the functional balance existing between positive and negative regulators of endothelial cell proliferation has paved the way to new therapeutic prospects.
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关键词
angiogenesis,vasculogenesis,vascular endothelial growth Factor (VEGF)
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