The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon

    Journal of cell science, Volume 119, Issue Pt 7, 2006, Pages 1307-1319.

    Cited by: 80|Bibtex|Views10|Links
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    Keywords:
    cell spreadingplcintegrinactinr-rasMore(6+)

    Abstract:

    R-Ras, an atypical member of the Ras subfamily of small GTPases, enhances integrin-mediated adhesion and signaling through a poorly understood mechanism. Dynamic analysis of cell spreading by total internal reflection fluorescence (TIRF) microscopy demonstrated that active R-Ras lengthened the duration of initial membrane protrusion, and ...More

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