Annual report of the National Influenza Surveillance Scheme, 2008.

M Kaczmarek,A Pengilley, Brian D Paterson, Russell D Owen,Chuanzhe Liu,Ian G Barr

Communicable diseases intelligence quarterly report(2010)

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摘要
The 2008 influenza season was moderate overall, with fewer laboratory-confirmed cases and influenza-like illness (ILI) presentations than in 2007, which was the most severe influenza season since national reporting of influenza began in 2001. In 2008, the number of laboratory-confirmed notifications for influenza was 1.9 times higher than the 5-year mean. High notification rates were reflected in an increase in presentations with ILI to sentinel general practices and emergency departments. Notification rates were highest in the 0-4 year age group. Unusually, the season was predominantly due to influenza B, with 54% of notifications being influenza B and 43% being influenza A (3% type unknown). The rate of influenza B was higher among the younger age groups, compared with influenza A, which was more common in the older age groups. Of influenza viruses circulating during the 2008 season, A(H3) viruses were predominant and were antigenically similar to the 2008 A(H3) vaccine strain, while the majority of A(H1) strains showed significant drift away from the 2008 A(H1) vaccine strain. There were approximately equal proportions of viruses from the 2 influenza B lineages B/Yamagata and B/Victoria.
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phylogeny,academic research,publishing,genetics,molecular evolution,genetic variability,infection control,commissioning,virology
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