Bone Marrow Plasma Cell Microaggregates Detected By Immunohistology Predict Earlier Relapse In Patients With Minimal Disease After High-Dose Therapy For Myeloma

HAEMATOLOGICA(2005)

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摘要
Plasma cell microaggregates detected by CD138 immunohistology were demonstrated in 22% of patients achieving morphologic remission 3 months after high-dose therapy for myeloma. Microaggregates were predictive of earlier disease progression, indicating that immunohistology may represent a useful tool in the assessment of minimal disease in patients after high-dose therapy for myeloma.
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