Design and construction of a high sensitivity self-shielded relaxometer

Daniel Hensley,Lisa Bauer,Patrick Goodwill,Zhi Wei Tay,Mark A Griswold,Steven M Conolly

Magnetic Particle Imaging（2015）

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摘要

An MPI spectrometer [1-3] measures the harmonics generated when a nonlinear SPIO is excited by a sinusoidal field. The harmonic peak spectrum allows for comparing SPIOs spatial resolution, since the harmonics are related to the modulation transfer function of the MPI imaging PSF [4-5]. It is also powerful to directly measure the point-spread function (PSF) by using the x-space MPI image reconstruction method [5-6], which has been shown to be equivalent to System Matrix reconstruction [7]. Here we describe a new design for an x-space relaxometer to increase sensitivity.

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关键词

biomagnetism,biomedical equipment,image reconstruction,iron compounds,magnetic particles,medical image processing,nanomagnetics,nanomedicine,optical transfer function,superparamagnetism,fe2o3,mpi imaging,mpi spectrometer,spios spatial resolution,generated harmonics,harmonic peak spectrum,high sensitivity self-shielded relaxometer,modulation transfer function,nonlinear spio,point-spread function,sinusoidal field,system matrix reconstruction,x-space mpi image reconstruction,x-space relaxometer

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