RSNA/QIBA: Shear wave speed as a biomarker for liver fibrosis staging

Timothy J Hall,Andy Milkowski,Brian S Garra,Paul L Carson,Mark L Palmeri, Kathy Nightingale,Ted Lynch, Abdullah Alturki,Michael P Andre,Stephane Audiere,Jeffery C Bamber, R G Barr, Jessica Bercoff,Miguel Bernal,Javier Brum,Huan Wee Chan,Shigao Chen, Claude Cohenbacrie,Mathieu Couade, Allison Daniels,Ryan J Dewall,Jonathan R Dillman,Richard L Ehman,Stephanie Franchiabella,Jeremie Fromageau,Jeanluc Gennisson, Jean Pierre Henry, Nikolas Ivancevich, Jan Kalin,S Kohn, Jennifer L Kugel,Ken Lee, N I Liu,Thanasis Loupas, Joan Mazernik,Stephen A Mcaleavey,Veronique Miette, Stephen Metz, B Morel,Thomas J Nelson, E Nordberg,Jennifer Oudry, Monali Padwal,Ned C Rouze,Anthony E Samir,Laurent Sandrin, Janet Schaccitti,Cedric Schmitt,Vijay Shamdasani,P Song, Pamela Switalski,Michael Wang,Keith A Wear,Hua Xie,Heng Zhao

Ultrasonics Symposium（2013）

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摘要

An interlaboratory study of shear wave speed (SWS) estimation was performed. Commercial shear wave elastography systems from Fibroscan, Philips, Siemens and Supersonic Imagine, as well as several custom laboratory systems, were involved. Fifteen sites were included in the study. CIRS manufactured and donated 11 pairs of custom phantoms designed for the purposes of this investigation. Dynamic mechanical tests of equivalent phantom materials were also performed. The results of this study demonstrate that there is very good agreement among SWS estimation systems, but there are several sources of bias and variance that can be addressed to improve consistency of measurement results.

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关键词

biomechanics,biomedical ultrasonics,diseases,dynamic testing,elastic waves,liver,phantoms,ultrasonic imaging,fibroscan,philips,rsna-qiba,siemens,supersonic imagine,biomarker,commercial shear wave elastography systems,custom phantoms,dynamic mechanical testing,equivalent phantom materials,liver fibrosis staging,shear wave speed estimation,materials

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