Chimpanzees as an animal model for human norovirus infection and vaccine development

    Proceedings of the National Academy of Sciences of the United States of America, Volume 108, Issue 1, 2011, Pages 325-330.

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    Keywords:
    immunohistochemistry

    Abstract:

    Noroviruses are global agents of acute gastroenteritis, but the development of control strategies has been hampered by the absence of a robust animal model. Studies in chimpanzees have played a key role in the characterization of several fastidious hepatitis viruses, and we investigated the feasibility of such studies for the noroviruses....More

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