EEG source localization in full-term newborns with hypoxic-ischemia.

EMBC(2013)

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摘要
The aim of this study was to evaluate EEG source localization by standardized weighted low-resolution brain electromagnetic tomography (swLORETA) for monitoring of fullterm newborns with hypoxic-ischemic encephalopathy, using a standard anatomic head model. Three representative examples of neonatal hypoxic-ischemia were included. The method was validated with MRI data. Hypoxic-ischemic areas, visible on MRI, correlated well with swLORETA current density distributions. In addition, neonatal seizure activity may be localized. The calculated current density distributions provide easy-to-interpret localized information about neonatal brain function, which may enable detailed longitudinal monitoring and potential assessment of treatment efficacy.
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关键词
mri data,paediatrics,tomography,diseases,electroencephalography,treatment efficacy assessment,patient monitoring,swloreta,eeg source localization,current density distribution calculation,standardized weighted low resolution brain electromagnetic tomography,physiological models,biomedical mri,hypoxic ischemic area,current density,hypoxic ischemic encephalopathy,full-term newborn monitoring,neonatal brain function,neonatal seizure activity localization,neonatal hypoxic ischemia,longitudinal monitoring,standard anatomic head model,head,brain mapping,magnetic resonance imaging,image segmentation,pediatrics
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