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Structure-based Discovery of NANOG Variant with Enhanced Properties to Promote Self-Renewal and Reprogramming of Pluripotent Stem Cells

Yohei Hayashi,Laura Caboni,Debanu Das,Fumiaki Yumoto,Thomas Clayton,Marc C. Deller,Phuong Nguyen,Carol L. Farr,Hsiu-Ju Chiu,Mitchell D. Miller,Marc-Andre Elsliger,Ashley M. Deacon,Adam Godzik,Scott A. Lesley,Kiichiro Tomoda,Bruce R. Conklin,Ian A. Wilson,Shinya Yamanaka,Robert J. Fletterick

The Molecular Biology Society of Japan（2016）

Cited 55|Views58
Key words
NANOG,crystal structure,pluripotent stem cells,DNA-binding,reprogramming
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