Blind deconvolution in dynamic contrast-enhanced MRI and ultrasound.

Radovan Jiřík,Karel Souček,Martin Mézl,Michal Bartoš,Eva Dražanová,František Dráfi,Lucie Grossová,Jiří Kratochvíla,Ondřej Macíček,Kim Nylund,Aleš Hampl,Odd Helge Gilja,Torfinn Taxt,Zenon Starčuk

EMBC（2014）

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摘要

This paper is focused on quantitative perfusion analysis using MRI and ultrasound. In both MRI and ultrasound, most approaches allow estimation of rate constants (Ktrans, kep for MRI) and indices (AUC, TTP) that are only related to the physiological perfusion parameters of a tissue (e.g. blood flow, vessel permeability) but do not allow their absolute quantification. Recent methods for quantification of these physiological perfusion parameters are shortly reviewed. The main problem of these methods is estimation of the arterial input function (AIF). This paper summarizes and extends the current blind-deconvolution approaches to AIF estimation. The feasibility of these methods is shown on a small preclinical study using both MRI and ultrasound.

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关键词

blood flow,haemorheology,blood vessels,quantitative perfusion analysis,biomedical ultrasonics,dynamic contrast-enhanced mri,blind-deconvolution approach,deconvolution,aif estimation,tissue,biomedical mri,preclinical study,ultrasound,physiological perfusion parameters,rate constant estimation,arterial input function estimation,medical image processing,vessel permeability,permeability,haemodynamics

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