High frequency stimulation of the STN restored the abnormal high-voltage spindles in the cortex and the globus pallidus of 6-OHDA lesioned rats.

Chen Yang,Jia-Rui Zhang,Lei Chen,Shun-Nan Ge,Jue-Lei Wang,Zhi-Qiang Yan,Dong Jia,Jun-Ling Zhu,Guo-Dong Gao

Neuroscience Letters（2015）

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摘要

•Dopamine depletion increased HVSs activity in the M1 cortex and the GP.•STN plays a role in HVSs modulation both in M1 cortex and GP.•STN high, but not low, frequency stimulation restored the abnormal HVSs.

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关键词

BG,DBS,ECoG,EPN,GP,HFS,HVSs,LFP,LFS,M1 cortex,6-OHDA,PD,PSD,SNr,STN,TH

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