A 4.78 mm 2 Fully-Integrated Neuromodulation SoC Combining 64 Acquisition Channels With Digital Compression and Simultaneous Dual Stimulation

A 65 nm CMOS 4.78 mm 2 integrated neuromodulation SoC consumes 348 μA from an unregulated 1.2 V to 1.8 V supply while operating 64 acquisition channels with epoch compression at an average firing rate of 50 Hz and engaging two stimulators with a pulse width of 250 μs/phase, differential current of 150 μA, and a pulse frequency of 100 Hz. Compared to the state of the art, this represents the lowest area and power for the highest integration complexity achieved to date.