Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans.

Talakad G. Lohith,Sami S. Zoghbi,Cheryl L. Morse,Maria D. Ferraris Araneta,Vanessa N. Barth,Nancy A. Goebl,Johannes T. Tauscher,Victor W. Pike,Robert B. Innis,Masahiro Fujita

NeuroImage（2014）

引用 30|浏览12

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摘要

[11C]NOP-1A is a novel high-affinity PET ligand for imaging nociceptin/orphanin FQ peptide (NOP) receptors. Here, we report reproducibility and reliability measures of binding parameter estimates for [11C]NOP-1A binding in the brain of healthy humans.

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关键词

AUC,BSMSS,fP,ICC,NOP,PET,WSMSS,VT

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