Polymethoxylated flavones potentiate the cytolytic activity of NK leukemia cell line KHYG-1 via enhanced expression of granzyme B.
Biochemical and Biophysical Research Communications（2015）
摘要
•Polymethoxylated flavones potentiate cytolytic activity of NK leukemia KHYG-1 cells.•The primary role of nobiletin in KHYG-1 cells is marked induction of granzyme B.•p38 MAPK is possibly involved in the induction of granzyme B in KHYG-1 cells.
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关键词
Granzyme B,KHYG-1,NK cell,Nobiletin,Polymethoxylated flavone,p38 MAPK
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