Influence of IL10 gene polymorphisms on the severity of liver fibrosis and susceptibility to liver cirrhosis in HBV/HCV-infected patients.

•We focused on the association of IL10 gene polymorphisms with liver fibrosis/cirrhosis.•The GCC haplotype may be associated with less severe liver fibrosis in CHB/C patients.•The -819T allele increased the risk of HCV-related liver cirrhosis in the Japanese.•We did not find any association for the IL10-1082A/G or -592C/A polymorphisms.