Toll like receptor 4 facilitates invasion and migration as a cancer stem cell marker in hepatocellular carcinoma.

Wen-Ting Liu,Ying-Ying Jing,Guo-Feng Yu,Zhi-Peng Han,Dan-Dan Yu,Qing-Min Fan,Fei Ye,Rong Li,Lu Gao,Qiu-Dong Zhao,Meng-Chao Wu,Li-Xin Wei

Cancer Letters（2015）

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摘要

•TLR4 expression was associated with the ability of invasion and migration in HCC.•TLR4 expression contributes to the stem-like properties of HCC cells.•The high expression of TLR4 is associated with clinicopathological characteristics and prognosis of HCC.

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关键词

CSCs,TICs,HCC,TLR4,LPS,K7,EpCAM,FBS,5-Fu

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