FAS/FASL-mediated cell death in the bovine endometrium.

Miki Arai,Shin Yoshioka,Ryo Nishimura,Kiyoshi Okuda

Animal Reproduction Science（2014）

引用 13|浏览1

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摘要

•Apoptosis-related factors, FAS, DcR3, BCL2 and BAX were expressed in bovine endometrium throughout the estrous cycle.•Treatment or pretreatment with TNF+IFNG in combination with FASL reduced viability in both epithelial and stromal cells.•Both extrinsic and intrinsic pathways are related to remodeling the bovine endometrium.•The death ligands play important roles in inducing cyclic endometrial apoptosis.

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关键词

Cattle,Endometrium,Remodeling,Apoptosis

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