Evaluation of aromatic amines with different purities and different solvent vehicles in the Ames test

Alexander P. Harding,Paul L.A. Popelier, James Harvey,Amanda Giddings, Graham Foster,Michael Kranz

Regulatory Toxicology and Pharmacology(2015)

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摘要
•Aromatic amines with different purities and different solvents were evaluated in the Ames test.•Aromatic amines were evaluated as the free base and hydrochloride salt in the Ames test.•The different permutations evaluated above had no impact on the Ames test outcomes.
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关键词
Ames test,Aromatic amines,Genotoxicity,Mutagenicity,DMSO solvent,Effect purification
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