Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis

    Cardiovascular research, pp. 284-294, 2015.

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    Keywords:
    angiogenesisendoglinextracellular matrixmatricellular proteintransforming growth factor beta

    Abstract:

    Secreted modular calcium-binding protein 1 (SMOC1) is a matricellular protein that potentially interferes with growth factor receptor signalling. The aim of this study was to determine how its expression is regulated in endothelial cells and its role in the regulation of endothelial cell function.SMOC1 was expressed by native murine endot...More

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