Role of CB2 receptors and cGMP pathway on the cannabinoid-dependent antiepileptic effects in an in vivo model of partial epilepsy.

Valerio Rizzo,Fabio Carletti,Giuditta Gambino,Girolamo Schiera,Carla Cannizzaro,Giuseppe Ferraro,Pierangelo Sardo

Epilepsy Research（2014）

引用 36|浏览2

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摘要

•Insight on non CB1 mediated antiepileptic activity of WIN;.•Evidence about CB2 involvement in WIN-mediated antiepileptic effects;.•Involvement of sGC pathway in the CBr system modulation of paroxysmal events.

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关键词

Cannabinoid,Temporal lobe epilepsy,AM630,sGC,Hippocampus,Electrophysiology

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