The CancerGrid experience

The CancerGrid approach to software support for clinical trials is based on two principles: careful curation of semantic metadata about clinical observations, to enable subsequent data integration, and model-driven generation of trial-specific software artefacts from a trial protocol, to streamline the software development process. This paper explains the approach, presents four varied case studies, and discusses the lessons learned. Summary, philosophy, and lessons of the CancerGrid project and follow-ons.Software support for cancer clinical trials, and similar data collection exercises.Metadata support, to enable subsequent meta-analysis.Model-driven generation of software artefacts to run trial.Four case studies.