14-deoxorapamycin, the microbial conversion product of rapamycin by Micromonospora chersina FIM03-712

In the course of searching for new rapamycin derivatives by microbial conversion, a microorganism, which was able to biotransform rapamycin into four products, was obtained and classified as Micromonospora chersina FIM03-712. One conversion product from the converted broth of the strain was isolated and purified. By means of physico-chemical properties and spectral analyses, it was identified with 14-deoxorapamycin.