A novel pH-sensitive (±)-α-tocopherol-5-fluorouracil adduct with antioxidant and anticancer properties.

Dong-Wei Li,Fang-Fang Tian,Yu-Shu Ge,Xin-Liang Ding,Jia-Han Li,Zi-Qiang Xu,Mei-Fang Zhang,Xiao-Le Han,Ran Li,Feng-Lei Jiang,Yi Liu

CHEMICAL COMMUNICATIONS（2011）

引用 11|浏览32

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摘要

A novel pH-sensitive (+/-)-alpha-tocopherol-5-fluorouracil (VE-5-FU) adduct with antioxidant and anticancer properties for antioxidant-based cancer chemoprevention was synthesized and utilized for selective drug release in the stomach.

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