Novel α-arylnitriles synthesis via Ni-catalyzed cross-coupling of α-bromonitriles with arylboronic acids under mild conditions.
ORGANIC & BIOMOLECULAR CHEMISTRY(2011)
摘要
An applicable and easy-handling Ni-catalyst can be used to promote direct arylation of alpha-bromonitriles with various arylboronic acids to construct alpha-arylnitriles under mild conditions. The methodology tolerates beta-hydrogens and functional groups in the substrates.
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关键词
arylboronic acids,synthesis,ni-catalyzed,cross-coupling
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