A new indene derivative from the marine fungus Phomopsis SP. (No. GX7-4A)

Yiguang Chen,Jiahui Pan,Fang Xu,Fan Liu,JianXiang Yang,Caihuan Huang,Chunling Xu,Yongjun Lu,Xiaoling Cai,Zhigang She,Yongcheng Lin

CHEMISTRY OF NATURAL COMPOUNDS（2010）

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摘要

new indene derivative named phomoindene A ( 1 ) and four known compounds were isolated from the marine fungus Phomopsis sp. (No. GX7-4A). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Preliminary pharmacological tests revealed that phomoindene A exhibited little cytotoxic activity towards KB, KBv 200, and MCF-7 cell lines.

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关键词

natural product,indene derivative,marine fungus,cytotoxic activity,prenyl,NMR assignment

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