Effects of electromagnetic pulse on the vimentin of mice testes

AIM To investigate the changes of the mice testes and the tight junction (Tj) relative molecular and to identify the molecular mechanisms of the mice blood-testis-barrier (BTB) permea-bility increasing after the mice were exposed to electromagnetic pulse (EMP). METHODS Observe the changes vimentin of the mice testes by laser scanning confocal technique. RESULTS After the 200kVm−1 EMP (the accumulative pulse times was 200) exposure, the vimentin in sustentacular cells of testis became irregularly shortened and derangement, and the intensity of immuno-fluorescence also showed ununiformity compared with control. CONCLUSION The increasing of mice BTB permeability perhaps caused by the changing of vimentin.