Bandunamide, A Novel Cyclopeptide From The Streptomyces Griseovariabilis Bandungensis

A new cyclic octapeptide, bandunamide, was isolated from the acetone extracts of streptomyces griseovariabilis bandungensis. This cyclic octapeptide exhibits strong antimicrobial activity against Phytophthora drechsleri (IC50=15 ng/mL), Colletotrehum higginsiannum (IC50=15.6 ng/mL), Piricularia oxyzae (IC50=0.2 mug/mL), and Fusarium oxysporum f. Sp. (IC50=100 mug/mL). The structure elucidation of bandunamide is herein reported.