Comparison of natural estrogens and synthetic derivative on genioglossus function and estrogen receptors expression in rats with chronic intermittent hypoxia.

•Estrogen-like compounds is involved in the study of treatments on sleep apnea.•A novel synthetic phytoestrogen derivative was first used in relieving muscle fatigue.•Resveratrol dimer exhibited better fatigue-protection than genistein and resveratrol.