Identification and characterization of the related immune-enhancing proteins in crab Scylla paramamosain stimulated with rhubarb polysaccharides.

•We found rhubarb polysaccharides could enhance crab Scylla Paramamosain immunity effectively.•5 related immune-enhancing proteins were identified.•A novel heomcyanin homologue with potential pathogen-resistant activities was further cloned and characterized.