Analysis of area strain of left ventricle antetheca in patients of hypertrophic cardiomyopathy with two-dimensional speckle-tracking imaging

Objective: To observe the myocardial area strain at the anterior wall (AW) of left ventricle (LV) in hypertrophic cardiomyopathy (HCM) patients with two-dimensional speckle-tracking imaging (STI). Methods: Twenty-five HCM patients (HCM group) and 25 healthy subjects (control group) were collected. Twenty-five ROIs on the AW of LV were tracked by STI. The strain (ε), strain rates in systole (SRS), strain rates in early-diastole (SRE), strain rates in late-diastole (SRA) on 25 ROIs were collected, and the mean valued of 25 ROIs were compared between the two groups. The correlation between the parameters of STI and left ventricular function were analyzed. Results: Compared with the control group, ε, SRS and SRE significantly decreased, but SRA increased in HCM group (all P<0.01). There were negative correlations between parameters of STI and left ventricular relative wall thickness and left ventricular mass index, respectively (all P更多