Detoxification of Jatropha curcas kernel cake by a novel Streptomyces fimicarius strain.

•The kernel cake was highly toxic even though the phorbol esters were undetectable.•An animal model was established to quantify the general toxicity of the kernel cake.•A new Streptomyces fimicarius strain was able to degrade the toxins by 97%.•The detoxified kernel cake was nontoxic to carp fingerling and improved plant growth.•Strain profile essential for the kernel cake detoxification was discussed.