Al 3+ /graphene composites for electrochemical detection of DNA cleavage

Herein, we present the electrochemical co-deposition of Al 3+ /graphene composites directly from an aqueous mixture containing graphene oxide (GO) and Al 3+ . The obtained Al 3+ /graphene composites with good electrochemical activity were regarded as an appropriate immobilization platform for double-stranded DNA (dsDNA). The nontoxic redox probe xanthurenic acid (XA) was successfully applied to recognize single-stranded DNA and dsDNA. We illustrated that the scission of dsDNA caused by GO combining with some metal ions could be detected by monitoring the electrochemical signals of XA.