DHTKD1 is essential for mitochondrial biogenesis and function maintenance.

Wangyang Xu,Houbao Zhu,Mingmin Gu,Qingqiong Luo,Jieying Ding,Yuting Yao,Fuxiang Chen,Zhugang Wang

FEBS Letters（2013）

引用 51|浏览39

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摘要

•DHTKD1 deficiency leads to mitochondrial dysfunction.•DHTKD1 deficiency impairs mitochondrial biogenesis.•DHTKD1 deficiency leads to ROS accumulation.•DHTKD1 is involved in cell proliferation and apoptosis.

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关键词

DHTKD1,Mitochondrial dysfunction,mtDNA,ROS,Cell apoptosis

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