MicroRNA-130b targets Fmr1 and regulates embryonic neural progenitor cell proliferation and differentiation.

Xi Gong,Kunshan Zhang,Yanlu Wang,Junbang Wang,Yaru Cui,Siguang Li,Yuping Luo

Biochemical and Biophysical Research Communications（2013）

引用 26|浏览19

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摘要

•We found that the 3′ UTR of the Fmr1 mRNA is a target of miR-130b.•MiR-130b suppresses the expression of Fmr1 in mouse embryonic stem cell.•MiR-130b alters the proliferation of mouse embryonic stem cell.•MiR-130b alters fate specification of mouse embryonic stem cell.

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关键词

Fmr1,miR-130b,Proliferation,Differentiation,Neural progenitor cells

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