Detection of effect of anti-nuclear antibody on spectrum of autoimmune liver diseases and spectral liver damage

The liver is a main organ involved actively in metabolism. The hepatocytes contain a variety of enzymes responsible for normal physiological functions. In the process of degeneration or necrosis, the enzyme is released into the blood and by measuring serum active enzymes, diagnosis of liver cell damage and estimate the degree of liver damage can be estimated. Autoimmune hepatitis is a chronic inflammation of the liver, and in sustained liver injury, there is the tendency of development of cirrhosis; caused by an abnormal immune response, chronic viral hepatitis. 65 cases of liver damage and 48 healthy persons as control were collected during January 2011 to August 2012., Anti-nuclear antibody for detection to observe positive rate in autoimmune liver disease spectrum were analyzed. This can be used in order to improve awareness of the disease and as primary prevention of disease.