A Protein-Based Ferritin Bio-Nanobattery

Nanostructured materials are increasingly important for the construction of electrochemical energy storage devices that will meet the needs of portable nanodevices. Here we describe the development of a nanoenergy storage system based on inorganic mineral phases contained in ferritin proteins. The electrochemical cell consists of an anode containing similar to 2000 iron atoms as Fe(OH)(2) in the hollow protein interior of ferritin and a cathode containing similar to 2000 of Co(OH)(3) in a separate ferritin molecule. The achieved initial voltage output from a combination of Fe2+-and Co3+-ferritins adsorbed on gold electrodes was similar to 500mV, while a combination of Fe2+-and Co3+-ferritins immobilized on gold produced a voltage of 350-405mV. When fully discharged, Fe(OH)(3) and Co(OH)(2) are the products of a single electron transfer per metal atom from anode to cathode. The spent components can be regenerated by chemical or electrochemical methods restoring battery function. The properties of ferritins are presented and their unique characteristics are described, which have led to the development of a functional bio-nanobattery.