Properties of xyloglucan hydrogel as the biomedical sustained-release carriers
Journal of Materials Science: Materials in Medicine(2012)
摘要
This study introduces an easy method of preparing xyloglucan hydrogel from xyloglucan, which is purified from tamarind seed gum. Xyloglucan hydrogel was prepared in 2 wt% solution by treating with β-galactosidase. Physical and chemical properties (molecular mass, size and viscosity) of xyloglucan hydrogel and xyloglucan solution were tested for a comparison. Experiments of drug release in vitro and in vivo were operated to investigate the potentialities of xyloglucan hydrogel as the biomedical sustained-release carriers for drug delivery system.
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关键词
Drug Release,Paracetamol,Dynamic Light Scattering,Drug Delivery System,Pullulan
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