HLA-G表达调控机制的最新研究进展

许惠惠
许惠惠
林爱芬
林爱芬

Journal of Medical Research, pp. 142-145, 2011.

Cited by: 1|Views5

Abstract:

<正>人类白细胞抗原-G(human leukocyte antigen G,HLA-G)属于非经典的HLAⅠ类分子,低多态性及限制性分布于免疫豁免组织是其最大特征。HLA-G能够直接抑制多种免疫活性细胞的生物学功能,包括抑制NK细胞的杀伤活性,抑制CTL介导的细胞溶解及抑制树突状细胞成熟等;诱导产生抑制性T细胞(suppressor T cells)和致耐受树突状细胞(tolero-

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ZHHLA-G表达调控机制的最新研究进展
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