HLA-G依赖的调节性细胞研究进展

许惠惠
许惠惠
林爱芬
林爱芬

Current Immunology, pp. 82-85, 2010.

Cited by: 4|Views3

Abstract:

人类白细胞抗原-G(human leukocyte antigen G,HLA-G)能够与免疫细胞上的抑制性受体(KIR2DL4、ILT-2、ILT-4)结合,直接发挥免疫抑制功能,是肿瘤细胞逃避机体免疫监视及免疫杀伤的有效手段。近来研究发现,HLA-G抗原通过诱导各种调节性细胞的产生发挥长效的免疫抑制效应。本文就HLA-G依赖调节性细胞的分类、表型及其免疫学功能作一综述。

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ZHHLA-G依赖的调节性细胞研究进展
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