The use of antibodies in diagnosis and therapy of cancer.

Immunology began as a study of the response of the living bodies to infections. Over the years, it has become progressively more basic, passing through phases of emphasis on serology, cellular immunology, molecular immunology and immunogenetics. Immunology has also grown to comprise many fields such as immunochemistry, immunopathology, immunopharmacology, allergy, clinical immunology, tumor immunology and transplantation. It has always provided an excellent mix of fundamental and applied sciences. The development of monoclonal antibody (MoAb) technology by Köhler and Milstein’ provided an enormous opportunity for examination of a range of issues, which previously seemed difficult to handle. MoAbs were used in immunocytopathology, radioimmunoassays, enzyme-linked immunosorbent assays, and flow cytometryin vitroandin vivofor diagnosis and immunotherapy of human disease.