Understanding the mechanism of sweet taste: Synthesis of tritium labeled guanidineacetic acids

Srinivasan Nagarajan,Michael S. Kellogg,Grant E. Dubois,David S. Williams,Christopher J. Gresk,Charles S. Markos

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS（1992）

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摘要

Syntheses of tritium labeled guanidineacetic acid sweetener and a tritiated photoaffinty labeling reagent via the catalytic hydrogenation of the dibromo intermediates are described. These labeled compounds were required for the investigation of sweet taste mechanism.

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关键词

TRITIUM LABEL,CATALYTIC REDUCTION,PHOTOAFFINITY LABEL,GUANIDINE SWEETENER,ANTIBODY ASSAY,SWEET TASTE MECHANISM

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