Comparative Genomic Analysis of Pancreatic Acinar Cell Carcinoma (PACC) and Pancreatic Ductal Adenocarcinoma (PDAC)Unveils New Actionable Genomic Aberrations in PACC.

Vaia Florou,Andrew Elliott,Matthew H Bailey, David Stone,Kajsa Affolter,Heloisa P Soares,Chris Nevala-Plagemann,Courtney Scaife,Phillip Walker,W Michael Korn,Emil Lou,Rachna T Shroff,Peter J Hosein,Ignacio Garrido-Laguna

Clinical cancer research : an official journal of the American Association for Cancer Research（2023）

引用 0|浏览16

暂无评分

摘要

There are major differences between PACC and PDAC, including downregulation of the MAPK signaling pathway, and less stromal cell abundance. In addition, genomic characterization of pure PACC revealed frequent targetable alterations, which can guide patient treatment.

查看译文

关键词

pancreatic acinar cell carcinoma,pancreatic ductal adenocarcinoma,new actionable genomic aberrations,pacc

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要