Chemoenzymatic enantioselective synthesis of 7-azabicyclo[2.2.1]heptane derivatives

Annie Michaud,Carine Lévesque,Michel Fila,Pierre Morin,Nicholas Pelchat,Robert Chênevert

Tetrahedron: Asymmetry（2011）

引用 5|浏览16

暂无评分

摘要

The enantioselective acylation (desymmetrization) of meso-7-azabicyclo[2.2.1]heptanediol 2 by vinyl acetate in the presence of Candida antarctica lipase B gave the corresponding (1R,2R,3S,4S)-monoester 4 in high enantiomeric purity (ee⩾98%).

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要