n-3 fatty acid deficiency increases brain protein synthesis in the free-moving adult rat.
Journal of neurochemistry(2002)
摘要
The autoradiographic method with L-[35S]methionine was used to determine the effects of an n-3 fatty acid deficiency on brain protein synthesis. Brain protein synthesis was significantly increased (from 50 to 150%) in 45 of the 52 brain structures studied in n-3 fatty acid-deficient rats as compared with control animals. Biochemical analysis confirmed the increase in overall rate of protein synthesis in brain as a whole.
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关键词
protein synthesis
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